---
title: How does AOAC interpret sample weight approval?
description: AOAC PTM Validations list weights next to matrix type, what does that mean?
---

[Skip to content](https://help.medicinalgenomics.com/en/how-does-aoac-interpret-sample-weight-approval#main-content)

[![MG\_LOGO-hi-rez-cropped.jpg](https://help.medicinalgenomics.com/hs-fs/hubfs/MG_LOGO-hi-rez-cropped.jpg?width=260&height=84&name=MG_LOGO-hi-rez-cropped.jpg)](https://medicinalgenomics.com)

- [Help Center](https://help.medicinalgenomics.com)
- [Web Store](https://store.medicinalgenomics.com)

Open main navigation

Close main navigation

- [Help Center](https://help.medicinalgenomics.com)
- [Web Store](https://store.medicinalgenomics.com)
- [Contact us](mailto:support@medicinalgenomics.com)

[Contact us](mailto:support@medicinalgenomics.com)

 How can we help you?

- There are no suggestions because the search field is empty.

1. [Help Center](https://help.medicinalgenomics.com/en?hsLang=en)
2. [Sample Purification](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en)
3. [AOAC](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en#aoac)

# How does AOAC interpret sample weight approval?

## AOAC PTM Validations list weights next to matrix type, what does that mean?

If you search approved methods on [AOACs Certified Method Website](https://members.aoac.org/aoac/ptm_validated_methods.aspx), the description of the method will list matrix type and weight.  See the example below:

![](https://help.medicinalgenomics.com/hubfs/image-png-Mar-14-2023-02-26-35-9618-PM.png)

The listed weights indicate the method is approved for UP TO the weight listed.  This does not mean you must test the weight listed.  In other words,  AOAC does allow certification of smaller test portions using the same dilution ratio as the validated test portion. 

For further reference please see the [AOAC Technical Bulletin](https://help.medicinalgenomics.com/hubfs/AOAC%20Tech%20Bulletins/AOAC_TB-2021-01_TestPortion%20Size%20-Dilution%20Ratio.pdf?hsLang=en) on the topic.

 

 

 

- [Frequently Asked Questions](https://help.medicinalgenomics.com/en/frequently-asked-questions?hsLang=en)
- [Product Updates](https://help.medicinalgenomics.com/en/product-updates?hsLang=en)
- [Sample Purification](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en#main-content)

    - [Grim Reefer Free DNA Removal](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en#grim-reefer-free-dna-removal)
    - [Internal Control](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en#internal-control)
    - [AOAC](https://help.medicinalgenomics.com/en/sample-purification?hsLang=en#aoac)
- [Early Detection Plant Screening](https://help.medicinalgenomics.com/en/early-detection-plant-screening?hsLang=en#main-content)

    - [FemINDICAtor® Plant Gender Testing](https://help.medicinalgenomics.com/en/early-detection-plant-screening?hsLang=en#femindicator-plant-gender-testing)
    - [PathoSEEK® Plant Pathogen Testing](https://help.medicinalgenomics.com/en/early-detection-plant-screening?hsLang=en#pathoseek-plant-pathogen-testing)
    - [Virus Assays](https://help.medicinalgenomics.com/en/early-detection-plant-screening?hsLang=en#virus-assays)
- [Genomic Services](https://help.medicinalgenomics.com/en/genomic-services?hsLang=en#main-content)

    - [StrainSEEK®](https://help.medicinalgenomics.com/en/genomic-services?hsLang=en#strainseek)
    - [Kannapedia](https://help.medicinalgenomics.com/en/genomic-services?hsLang=en#kannapedia)
- [Microbial Safety Testing](https://help.medicinalgenomics.com/en/microbial-safety-testing?hsLang=en#main-content)

    - [Hardware and Consumables](https://help.medicinalgenomics.com/en/microbial-safety-testing?hsLang=en#hardware-and-consumables)
    - [Validation](https://help.medicinalgenomics.com/en/microbial-safety-testing?hsLang=en#validation)
    - [PathoSEEK](https://help.medicinalgenomics.com/en/microbial-safety-testing?hsLang=en#pathoseek)
    - [Aspergillus](https://help.medicinalgenomics.com/en/microbial-safety-testing?hsLang=en#aspergillus)
- [Mic qPCR Instrument](https://help.medicinalgenomics.com/en/mic-qpcr-instrument?hsLang=en)
- [AriaMx](https://help.medicinalgenomics.com/en/ariamx?hsLang=en)
- [Product Specifications](https://help.medicinalgenomics.com/en/product-specifications?hsLang=en)

- [Contact Support](mailto:support@medicinalgenomics.com)
- [Sign Up for Our Newsletter](https://share.hsforms.com/1rFnAme5nTYuGeU0IdkMQGA20xr2)
- [Join Us at CannMed 26](https://cannmedevents.com)

[![MG\_LOGO-hi-rez-cropped.jpg](https://help.medicinalgenomics.com/hs-fs/hubfs/MG_LOGO-hi-rez-cropped.jpg?width=260&height=84&name=MG_LOGO-hi-rez-cropped.jpg "MG_LOGO-hi-rez-cropped.jpg")](http://www.medicinalgenomics.com)

Medicinal Genomics Help Center

<https://www.instagram.com/medicinal.genomics/> <https://twitter.com/MediGenomics> <https://www.facebook.com/FreeCBD> <https://www.linkedin.com/company/medicinal-genomics/> <https://www.youtube.com/@medicinal.genomics>

Copyright © 2026, Medicinal Genomics